{
  "source": "universum.earth",
  "author": "Dr. Vladimir Pereligyn",
  "updated": "2026-02-08",
  "conditions": [
    {
      "name": "Type 2 Diabetes Mellitus",
      "nameRu": "Сахарный диабет 2 типа",
      "icdCode": "E11",
      "description": "A metabolic disorder characterized by insulin resistance and relative insulin deficiency, leading to chronic hyperglycemia. The most common form of diabetes, typically associated with obesity, sedentary lifestyle, and genetic predisposition.",
      "treatedBy": "md_pereligyn protocol",
      "successContext": {
        "remissionRate": "85% in 3-6 months",
        "hba1cReduction": "8.2% → 5.6% (mean)",
        "medicationFree": "92% stop metformin",
        "weightLoss": "14 kg average in 4 months"
      }
    },
    {
      "name": "Prediabetes",
      "nameRu": "Преддиабет",
      "icdCode": "R73.03",
      "description": "A condition where blood sugar levels are higher than normal but not yet high enough to be diagnosed as type 2 diabetes (HbA1c 5.7-6.4%). Without intervention, most people with prediabetes develop type 2 diabetes within 5-10 years.",
      "treatedBy": "md_pereligyn protocol",
      "successContext": {
        "remissionRate": "95%+ in 2-3 months",
        "preventsDiabetes": "Early intervention prevents progression to T2D",
        "timeline": "Fastest results of all subgroups"
      }
    },
    {
      "name": "Insulin Resistance",
      "nameRu": "Инсулинорезистентность",
      "icdCode": "E88.81",
      "description": "A condition where cells in the body don't respond effectively to insulin, requiring the pancreas to produce more insulin to maintain normal blood glucose. The root cause of type 2 diabetes, metabolic syndrome, and PCOS. Measured by HOMA-IR index and fasting insulin levels.",
      "treatedBy": "md_pereligyn protocol",
      "successContext": {
        "homaIrReduction": "6.8 → 1.9 (mean, -72%)",
        "fastingInsulinReduction": "24.3 → 8.7 μIU/mL (-64%)",
        "mechanism": "Core target of the Protocol — eliminates the root cause"
      }
    },
    {
      "name": "Metabolic Syndrome",
      "nameRu": "Метаболический синдром",
      "icdCode": "E88.81",
      "description": "A cluster of conditions occurring together — central obesity, high blood pressure, high triglycerides, low HDL cholesterol, and elevated fasting glucose — that increase the risk of heart disease, stroke, and type 2 diabetes.",
      "treatedBy": "md_pereligyn protocol",
      "successContext": {
        "triglyceridesReduction": "218 → 112 mg/dL (-49%)",
        "hdlIncrease": "38 → 52 mg/dL (+37%)",
        "bloodPressureReduction": "142 → 126 mmHg systolic",
        "waistReduction": "108 → 94 cm (-13%)"
      }
    },
    {
      "name": "Non-Alcoholic Fatty Liver Disease (NAFLD)",
      "nameRu": "Неалкогольная жировая болезнь печени (НАЖБП)",
      "icdCode": "K76.0",
      "description": "Accumulation of fat in the liver not caused by alcohol consumption. Strongly associated with insulin resistance and type 2 diabetes. Can progress to NASH (non-alcoholic steatohepatitis), cirrhosis, and liver failure.",
      "treatedBy": "md_pereligyn protocol",
      "successContext": {
        "altNormalization": "86% of NAFLD patients",
        "liverFatReduction": "79% improvement on ultrasound",
        "completeResolution": "68% of patients",
        "altReduction": "42 → 24 U/L (mean)"
      }
    },
    {
      "name": "Polycystic Ovary Syndrome (PCOS)",
      "nameRu": "Синдром поликистозных яичников (СПКЯ)",
      "icdCode": "E28.2",
      "description": "A hormonal disorder common in women of reproductive age, characterized by irregular periods, excess androgen levels, and polycystic ovaries. Insulin resistance is present in 70-80% of PCOS patients and is considered a key driver of the condition.",
      "treatedBy": "md_pereligyn protocol",
      "successContext": {
        "insulinResistanceImprovement": "92% of PCOS patients",
        "menstrualRegulation": "78%",
        "ovulationRestoration": "64%",
        "weightLoss": "11.8 kg average in 6 months"
      }
    },
    {
      "name": "Obesity (associated with insulin resistance)",
      "nameRu": "Ожирение (ассоциированное с инсулинорезистентностью)",
      "icdCode": "E66.0",
      "description": "Excessive body fat accumulation that presents a risk to health. In the context of type 2 diabetes, obesity is both a cause and consequence of insulin resistance — high insulin levels promote fat storage, creating a vicious cycle.",
      "treatedBy": "md_pereligyn protocol",
      "successContext": {
        "meanWeightLoss": "14.2 kg in 6 months",
        "bmiReduction": "4.8 kg/m² average",
        "over10kg": "72% of patients lose >10 kg",
        "over20kg": "28% of patients lose >20 kg",
        "mechanism": "Weight loss is natural — no calorie restriction, no hunger"
      }
    }
  ]
}