MD_PERELIGYN — Holistic & Integrative Medicine — Dr. Vladimir Pereligyn
Ways to Work Together
Four formats — from a lab review to a full month of supervision. Card payment (EUR), works from most countries.
Lab Review
€100
Review of your lab results with prescriptions based on them.
- Written summary of your lab results
- Prescription list
- Recommendations for further testing
Consultation + Follow-up Review
€250
Full review → prescriptions → follow-up review → recommendations.
- Full review of your condition and labs
- Prescription list
- Follow-up review of control labs
- Final recommendations
2-Week Support
€500
Two weeks of work with the team + a nutritionist on board.
- Everything in Consultation + Follow-up Review
- Two weeks of active supervision
- Nutritionist consultation and guidance
- Plan adjustments along the way
VIP — Full Month
€1,000
30 days of full supervision: doctor, nutritionist, and specialist consultations arranged for you.
- Intake form and electronic medical record
- Clinical assessment and lab test list
- Health map and root-cause identification
- Personalized treatment plan and prescription list
Health Shop
Detailed Treatment Programs
Personalized recovery protocols for complex medical conditions
Diabetes Treatment
Comprehensive treatment for type 1 and type 2 diabetes
Burnout Treatment
Comprehensive recovery from emotional and physical exhaustion
Anti-aging Program
Slowing aging processes and optimizing longevity
Medical Tourism
News and Articles
Current materials on health, holistic medicine and my programs

Psilocybin for depression: what 20 years of research shows, and what changed in 2026
In twenty years psilocybin went from laboratory curiosity to publications in NEJM and JAMA. But in May 2026 the largest and best-blinded trial — EPISODE (n=144) — missed its primary endpoint: 17.0% response versus 10.6% on active placebo. Here is what the evidence actually supports, where the methodology strains, and why an endocrinologist looks at the thyroid first in "treatment-resistant" depression.
July 30, 2026
Which Mental Illness Is Linked to Hypothyroidism? Depression, Anxiety, and Hashimoto's
A patient has been on antidepressants for five years with no lasting effect — nobody ever checked TPO antibodies. A case-control study found the lifetime odds of depression are 6.6× higher, and generalized anxiety disorder 4.9× higher, in patients with euthyroid Hashimoto's — with completely normal TSH and fT4. I review exactly which mental illnesses are linked to thyroid disease, the mechanism, and when adding T3 works as an antidepressant strategy.
July 7, 2026
Best Liver Supplement for Fatty Liver: What's Actually Proven — Vitamin E, Silymarin, NAC
Pharmacy shelves are full of "liver support" supplements with zero controlled trials behind them. Of that entire market, only three substances have randomized placebo-controlled data specifically in fatty liver disease: vitamin E 800 IU/day (PIVENS, biopsy-confirmed improvement), silymarin 2100 mg/day, and N-acetylcysteine 600 mg twice daily. I review the doses, the evidence quality, and who these protocols are not for.
July 7, 2026Low-Dose Naltrexone (LDN) for Fibromyalgia: Dosing, Evidence, What to Expect
Fibromyalgia has the strongest evidence base of any low-dose naltrexone (LDN) indication. A randomized crossover trial (Younger 2013) showed a 28.8% pain reduction versus 18.0% on placebo at 4.5 mg. I review the microglia mechanism, realistic titration, and the honest limitations of this evidence.
July 7, 2026
Cognitive Aging: How to Recognize It in Your Thinking Before Others Do
The brain gives no pain signal when it is being lost. I break down the psychological markers of cognitive aging — executive dysfunction and subjective complaints that precede memory loss by years — and what is actually proven to help.
July 2, 2026
Active Surveillance for Thyroid Cancer: When Cancer Does Not Need Immediate Surgery
There are small thyroid cancers that do not need to be operated on immediately. Instead of surgery, the physician offers active surveillance — regular monitoring by ultrasound. This is not a refusal of treatment but a proven strategy with more than 30 years of history. We explain who it is suitable for and why it is safe.
June 25, 2026
TSH Is a Pituitary Hormone, Not a Thyroid Hormone: The Single-Test Blind Spot
When a clinician orders "just TSH" — they measure pituitary function, not thyroid function. TSH is a late, inertial marker: it reflects chronic imbalance, not acute dysfunction. Estrogens, biotin, non-thyroidal illness, circadian rhythm — all shift the number without changing thyroid status. Here is the full panel and the decision principle.
June 2, 2026
T3 — the Only Active Thyroid Hormone: Why It Works Inside the Cell
T3 is the only thyroid hormone that actually works. And it works not in blood but inside the cell, at the nuclear receptor. Blood is only a transport phase. Some women with normal TSH have cellular hypothyroidism and suffer with full symptoms despite "normal" labs. Here is the biology of T3, T4→T3 conversion, the hidden forms of deficiency, and the full laboratory panel.
June 2, 2026
Hypothyroidism Treatment Beyond Thyroxine: Conversion, Cofactors, Cortisol
The patient has been on levothyroxine for five years, TSH is normal — yet hypothyroid symptoms persist. This is not "poor compliance"; it is a systems failure: peripheral T4→T3 conversion, membrane transport, cofactors, cortisol, gut. We break down what general practice misses and what protocol actually works — with PMIDs, doses, and 8-week control markers.
June 2, 2026
Stress and the Thyroid: Three Levels of Suppression and the fT3/rT3 Protocol
TSH normal, free T4 normal, and the patient is falling apart with fatigue, cold intolerance, weight gain, and broken sleep. The classic "your labs are fine" trap. In reality, chronic stress shuts the thyroid down at three different levels, and you only see it on a properly built panel: fT3, rT3, salivary cortisol, ferritin, selenium. Here is the mechanism, the exact numbers, and an 8-week recovery protocol.
June 2, 2026
Thyroid After Virus: Three Scenarios — Subacute Thyroiditis, Autoimmune Shift, NTIS
Two to six weeks after an acute viral infection, the patient returns with "I am not myself" complaints: palpitations, sweating, anxiety — or the opposite, fatigue, edema, apathy. The post-viral thyroid can follow one of three clinically distinct paths. Treatment for each is different. Blanket therapy makes things worse. This review covers how to tell the scenarios apart, what to measure, and when not to prescribe levothyroxine.
June 2, 2026
Anti-TPO: The Main Marker of Hashimoto's Thyroiditis and How to Interpret It
Anti-TPO antibodies are the key to diagnosing autoimmune thyroiditis — but not a treatment target and not a reason for repeat testing. Here is when the test changes management, how to read the titer (35 / 100 / 1000 IU/mL), why an isolated positive without ultrasound and clinical signs is a lab finding rather than Hashimoto, and where selenium actually reduces antibody levels by 30–40%.
June 2, 2026